The International Space Station (ISS) is a modular space laboratory in low Earth orbit, jointly operated by NASA, Roscosmos, ESA, JAXA, and CSA. Launched beginning in 1998, it has been continuously inhabited since November 2000 and supports cutting-edge research in microgravity, Earth observation, and space technology, while fostering international cooperation.
Source: nasa.gov
02/04/2011

First flown in 1992, Endeavour, the youngest space shuttle orbiter, is being prepared for its 25th and final trip to low Earth orbit. Seen here from an exciting perspective 400 feet above the floor of Kennedy Space Center's Vehicle Assembly Building, Endeavour (OV-105) is mated to an external tank and solid rocket boosters just prior to roll out to launch pad 39A on March 11. The completed space shuttle stands over 18 stories tall. Intended for an April 19 near sunset launch on STS-134, Endeavour will head for the International Space Station and deliver the AMS cosmic ray experiment. The final flight of Endeavour will be the penultimate planned space shuttle flight.